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Weight loss peptides are short chains of amino acids that play a role in regulating various bodily functions, including metabolism and appetite. They're naturally occurring in the body but are also being synthesized for therapeutic purposes, including weight management. Their impact on the health industry is significant and evolving.

Types and Mechanisms: Several peptides are being researched and used, each with its own proposed mechanism of action: GLP-1 Receptor Agonists (e.g., Exenatide, Liraglutide): These peptides mimic the effects of glucagon-like peptide-1, a hormone naturally released after eating. GLP-1 slows gastric emptying, increases satiety (feeling full), and improves insulin secretion. This leads to reduced food intake and improved blood sugar control, contributing to weight loss. They are approved for treatment of type 2 diabetes and are increasingly used off-label for weight management due to their significant weight loss effects. Ghrelin Receptor Antagonists: Ghrelin is a hormone that stimulates appetite. Antagonists block the effects of ghrelin, reducing hunger and promoting weight loss. Research in this area is ongoing, with some promising results. Peptide YY (PYY): This peptide is released in the intestines after eating and signals satiety to the brain. Synthetic PYY is being studied for its potential to increase feelings of fullness and reduce caloric intake. Other Peptides: Many other peptides are being explored for their potential role in weight loss, including those affecting fat metabolism, energy expenditure, and brown adipose tissue (BAT) activity. However, research on these is still in earlier stages.